Volume 284, Number 5411 Issue of 2 Apr 1999, pp. 80 - 81
©1999 by The American Association for the Advancement of Science.

COMPLEX SYSTEMS:
Building Working Cells 'in Silico'

Dennis Normile

A computer scientist and biologist has come up with a scheme for exploring the effects that only emerge when a cell's many processes interact: a simulation program called E-CELL that can reproduce, in simplified form, a cell's biochemical symphony. Other computer models of the cell are being developed that reproduce individual cellular processes in detail; E-CELL, in contrast, is designed to paint a broad-brush picture of the cell as a whole.

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